I've recently experienced a problem with my clicking/dragging on my Macbook Pro (V10.8.5) after editing a single large photo on Photoshop CS6. In the process of editing, the main problems which surfaced and are currently encountered are as follows: The drop down items under the menu bar is no longer highlighted as the mouse hovers over each item. Items from the menu bar may require to be clicked twice. Clicking on applications from the dock leaves the description frozen unless clicked otherwise. Mouseover in text fields doesn't result in the appropriate cursor being generated; mouseover on hyperlinks and tabs also doesn't work (more of a lag in change of cursor until it is clicked otherwise. Controls from Quicktime Player which automatically hide doesn't show up during mouseover unless clicked for multiple times (this may occur for other items which are configured to be automatically hidden and shown such as the dock) Previews on Photoshop no longer work and saving requires a much longer time, sometimes indicating the saving of a file at 0% until otherwise clicked elsewhere on the Photoshop window. Here's a short uploaded screen recording of some of the above stated problems: http://youtu.be/WUNGUSPgkY0 I've tried doing the following: closing Photoshop and reopening it; resizing and re-editing the photo on a smaller scale; restarting my Mac; executing 'killall Finder' via Terminal; resetting the PRAM However, the problem still remains. It makes it really difficult to perform tasks on my Mac efficiently since there needs to be many unexpected clicks. Anyone encountered a similar situation before? Any effective solutions to the problem will be greatly appreciated.