I have a MacPro 3,1 here at work and it basically stays on 24/7. I notice that every few days however, I have to reboot the machine to get back memory and make things run smoothly again, because the "free" amount on Activity Monitor will be under 100MB, and they'll be a bunch of page-ins and page-outs. I have 12GB of RAM in here and there's nothing special on this machine, just Final Cut Studio and VMWare Fusion, but again, every few days it starts to run like garbage until I reboot and sweep all the RAM clean. Most of it stays under the inactive section (3-5GB), but just trying to do things like load the VM again is painfully slow. Suggestions?