I always wonder about the drawbacks quite frankly. A RAID controller goes out and all those drives are dead unless you can get that SAME EXACT model controller. Drives are not necessarily exact data duplicates of each other so that they can't be used as standalones (say you separate them out for some reason) I've been running a 1TB in-tower with frequent backups to an external USB 1TB to minimize hardware in between. Now I'm keeping an eye on Thunderbolt and I see many of the mass data backup solutions utilizing RAID protocols in their enclosure setups. Not sure how to follow all this now lol.