This is with the latest Orochi drivers and OSX 10.6.4 (and 10.6.3). Whether the Orochi is plugged in via USB or Bluetooth, it will not automatically switch between my customized Profiles when I launch the associated programs. The "Auto Switch" radio box is checked for the Profiles in question. Is there any resolution to this? I also find that macros I've set up often disappear. Some stay in place, but others consistently vanish. Any fix for this as well? Thank you.