Maybe....
Faronics (the folks that sell Deep Freeze) say that CoreStorage volumes have to be reverted before installing Deep Freeze.
https://faronics.kayako.com/Knowled...lling-deep-freeze-mac-on-core-storage-volumes.
(reverting is removing the core storage virtual drives, so that would mostly be the same effect as turning CoreStorage off.)
Also, Deep Freeze cannot be installed on a Fusion drive, which would also need to be reverted. That's not always something that the typical user would want (or need).
And, Deep Freeze can't be used with an AFPS-format drive, which pretty much prevents its use on a lot of Macs running High Sierra.
I don't think you can connect all that to any additional vulnerability, just by reverting CoreStorage volumes.
But, you would lose whatever benefits are derived from using the CoreStorage technology