Very old thread, I know, but I was wondering if anyone monitoring this thread has any experience with the PL-2303 and VMware Fusion? I use this quite often connecting to other devices, and it seems that there could be a timing issue with Windows XP, 7, or 8.x as the guest OS. Has anyone compared the PL-2303 with a driver in OS X and passthrough a Serial port to the VM, or, as I have done, passed the USB device through to the VM and installed the PL-2303 driver in there.
This would be strictly for a notebook and not a desktop.
Thanks!