-Spotlight has had an off and on relationship with the "Apps using Significant Power" spot. At first, it was because it was indexing again. Then it stopped, and even a restart quickly had it using a larger amount of power
-Shutdown is slower than in Mountain Lion for me. This might not be a bug, but I hope it is.
-When I put in "WebKit" into my Spotlight (which the nightly doesn't work yet folks, but that's expected), I get multiple versions of it that do nothing. Seriously, they open up to saying that the application isn't there. Kind of afraid to delete any of them, though, on the off chance that one of them is powering the main Safari.
Small things, not enough to make me want to go back. It looks nice, responds nice, and is overall better than Mountain Lion already. Also, Maps is a bit slow to open... but that's just nitpicking.