Safari Unresponsiveness

Seems that ever since I've been using El Capitan it seems, Safari has been acting unresponsively. Usually, it won't happen while I am using it, but after I step away from the computer for a bit and come back to it beachballed / unresponsive. Sometimes force quitting / attempting to relaunch will make my whole computer unresponsive and I will have to restart. Any ideas as to what could be causing the issue / how to diagnose? I've poured over Console, but nothing seems too out of the ordinary (except, "process Safari[4067] thread 5628772 caught burning CPU!; EXC_RESOURCE supressed due to audio playback", but nothing is playing). Any other ideas would be greatly appreciated!

System Details:
iMac / MacBook
OSX El Capitan 10.11.4
Safari Version 9.1 (11601.5.17.1)

Extensions:

 

I've disabled them all. Hopefully I can figure it out by re-enabling each one one at a time, albeit a tedious process. Is there a console for the extensions specifically or other tool for such a purpose?

I've tried to do this, nothing really seems to stand out in the Acivity Monitor. No media is playing or was left playing before I left my computer

--- Post Merged, Apr 30, 2016 ---

Again, it's never been unresponsive while using, it always happens when I put my computer to sleep and re-log back in (MacBook) or step away from my machine for a bit, it auto locks, then upon coming back to the machine it becomes responsive (iMac).