Changes due to atmospheric conditions, sure. But, as the moon is tidal locked to the earth, there’s only one side that can be seen from earth.Each full moon looks different because...wait for it...the moon rotates. There is also the color change do to atmospheric conditions--everything from yellow to red to purple to grey.

Tidal Locking - NASA Science
The same side of the Moon always faces Earth, because the Moon rotates exactly once each time it orbits our planet. This is called synchronous rotation.
