Software update hung, now Apps won't work

[robmax72]

first the specifics:
I have a MacPro:
Version 10.6.2 for OSX

I did the latest update that showed for Safari. It went to reboot and just sat there and hung. I waited for 10 minutes, then manually restarted the Mac. It came up, but then when I went to open Mail, I got an error that it couldn't open. I then clicked on ok, and tried to open another app, and it wouldn't open. I tried with several apps with the same result.

I downloaded the MacOSXUpdCombo10.6.2.dmg and ran it with no problems, and the Apps will still not open.

Any idea's?

 

[robmax72]

The only app that seems to work at this point is my firefox, which makes it real weird.

 

[gglockner]

Try to create a new user and see if you can open mail for the new user.

 

[rickvanr]

repair permissions?