Bizarre issue started occurring to me this week, wondering if anyone else is experiencing it too. It's only noticed when I'm loading up a YouTube video; it plays normally, then randomly the sounds stops. Quitting the app and testing other audio throughout the system shows that audio has stopped completely; music can't be heard, keyboard clicks go silent, ringtones don't play. A reboot is then required to return everything to normal. This started occurring after I did a clean restore to iOS 10.1.1 via iTunes (but before the updated 10.1.1 was released a few days ago). It never happened before that point, even on the 10.2 beta. If it's a common bug I'll just wait it out (it's a PITA to restore to a 256gb phone), but if not, I'll bite the bullet and hit restore again. Please do chime in if you can.