Well, here's my update - I'm currently typing this on my Macbook 2,1 with the Samsung 840 SSD installed as the primary drive.
The install was SUPER simple - just popped the SSD in place of the HDD, and booted to my Snow Leopard disc. Ran Disk Utility, formatted the SSD, and started the install. Currently downloading Lion from the Mac App store as I type this.
System is very fast - startup/shutdown is amazing. Applications (what's here, I haven't installed everything yet - waiting to get Lion on first) open super quickly.
Already VERY happy with this upgrade. My MacBook lives on...
EDIT: Make sure to download Trim Enabler, activate it and reboot. As others have reported, TRIM is not enabled without doing this step (you can see it will say "TRIM Support: No" in System Profiler until you activate it).