I used to have a 80gb Intel SSD (The very very early models, with defrag problems), but that totally stopped working after around 6 months of usage - It just died off. It was fixed the first time by writing zeros to the drive, but the drive died again soon after 7 days. Couldn't be fixed at that point -
I'm now using a 64GB SSD as my primary drive on my Macbook c2d (white), and it has been working perfectly for almost a year - recently, OSX has started to lag really bad, at random times for a prolonged period of time (sometimes 10 seconds, sometimes 30, 40, 50.. etc.), although the drive still performs extremely quickly.
So, I booted from my SuperDuper! clone, and wrote zeros on the SSD and restored the data from my external clone onto the SSD. The freezes seemed to have shortened, but I'm still unsure wether it's a software problem or a hardware problem.
You wouldn't need to 'reclone' your SSD frequently, around once every 8~12 months should be fine (at least, for me).
But until OSX has TRIM support, I'm not gonna put a SSD into the new MBP i5 that I ordered