I wholeheartedly agree that SSDs are orders of magnitude faster than HDD's- I'm just not sure the performance gain on RAID 0 would be that big, if any, considering the differentiation is the elimination of seek time and thus the boosting of IOPS, not raw speed (although SSDs do well there too).
There isn't really a significant price advantage to multiple smaller ones, also, you're talking about big bucks when you're doing more than 200GB of SSD storage in the first place. I like the two drive system, as for now, it provides me with the speed I desire for relatively minimal cost and large storage. At the current prices, it would be downright wasteful to have a large iTunes library and photo collection on an SSD. VMs, the OS, and applications, however, benefit hugely from the SSD.