Hello- I am posting this for my cousin in an effort to get some more solutions that I can help her try. I am an experienced user, but nothing is sticking out to me as being really "WRONG" per se. She has a 1st gen 1.8ghz MacBook w/ 2gb ram and about 4gb of free hard disk space (I feel this could be a root of the problem) This is the the email I got from her today... Recently, my notebook has been, for lack of a better term, freaking out. If I try to open any application, the pinwheel comes up for a while. Every time I try to open iTunes it tells me that the application failed and asks if I want to quit, reopen, or report the problem. I gave up trying to open iPhoto because the pinwheel comes up anytime I try to scroll up and down to look at pictures. My photobooth randomly stopped showing up at all...I clicked on it once, and it bounced for a while, and then stopped but the application didn't appear. Then it disappeared from my navigation bar. I found it in my applications, launched it to put it back on the bar, and now when I click on it it jumps once and then stops and nothing happens. The latest development is that I have no wireless connectivity I can't connect to iChat, Firefox, or Safari. FYI: I had her set up to use internet connection sharing via her parents iMac 24" when she is home from school I am looking for anything to tell her to try to check beyond repairing permissions. Thanks!