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i've got the same problem.. It first happened to me when i edited contacts on the iPod. I just waited it out, and it finally finished syncing, but i seriously dont have this kind of time. It literally took an hour to sync with iTunes. Is this yet another software glitch or what?
 
Have you jailbreak'd your iPod? Because when I installed the iPhone mail application it wouldn't sync I had to uninstall it and then reinstall.
 
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