We'll, I'm in bed, and the Air is no more difficult to use than the Mini. I gave up on the iPad 4 after a couple of brutal attempts. It's easy enough to hold with one hand, but one hand and resting on my chest is better (this is a flat on my back test ). I'm beginning to see the Mini fading out of my life. My HTC One and its 4.7" screen can take on the small tablet role for a while. If that doesn't work, I'll look at the retina Mini.