Wired did a take on NYT's Times Reader. In a way, the application is sort of a retropulsion of the App Store concept -- the app store demonstrated that specialized apps could deliver a superior experience to the web browser for getting some kinds of data while on the go. NYT's own application is one excellent example. This, however, is a desktop application that runs in Adobe AIR on top of Windows, OS X, or Linux. It has a very simple installation via Flash and it looks lovely. EDIT: Interestingly, in Windows XP, it can install itself onto a computer with administrative privileges, if Flash is already installed (but AIR is not). In Linux, in contrast, it required a sudo password. Have not tried it yet in OS X.