Unable to run .exe file in Stuffit Expander.

I am trying to setup tvants on my mac to watch baseball here in Australia and have run into a problem when i try to open my tvantssetup.exe file through Stuffit Expander. I get the following message:

The file "/Users/jeremyinnes/Desktop/tvantssetup.exe" does not appear to be compressed or encoded. It is advised that you obtain further information about the contents of this file from the sender or provider of the file.

What can I do here? I have tried to find other programs to open/run my .exe files but have had no luck. Please advise.

jinnes