Unclickable area problem

[JayInNJ]

I have a 2015 13" MacBook Pro that is up to date with Sierra. For at least a year now I will occasionally get a "dead zone" or unclickable area that doesn't respond to any mouse actions. It is close to the middle of the screen but not exactly. Which ever app is active will not respond to and mouse clicks or scrolling in that area. If I move the app slightly I can then click in that area. It happens with all applications. It will resolve itself after a reboot and eventually come back. It seems to only occur when using an external monitor but that might just be because I use one 90% of the time. I am guessing some weird software thing is happening where it thinks there is a window in that area and button clicks are being sent to something else.

Anyone ever see something like this before and fix it?

 

[casperes1996]

Anyone ever see something like this before and fix it?

No, never had anything like this happen. Though we can sort of test your hypothesis.
When it happens, try clicking cmd+shift+4. Then space. Now you're in "window screenshot mode", where anything you click will be a screenshot of only the selected window. Now hover over the dead area, and see if it shows as if there's a window there.
Not exactly bulletproof by any stretch of the imagination, but first thing I came up with

 

[jobs.jdfournier]

Thanks, good idea. Unfortunately right now it is not doing it. One workaround I found was to use a different desktop. The problem seems isolated to desktop 1.

 

[casperes1996]

Thanks, good idea. Unfortunately right now it is not doing it. One workaround I found was to use a different desktop. The problem seems isolated to desktop 1.

When it happens you could also try running "killall Dock" and seeing if it fixes it then. If it's only on Desktop 1 could be related to Mission Control and thereby Dock.