I've been using a Belkin USB-C to Minidisplayport cable for my 32" BenQ QHD screen on my 2018 Mini for almost three years, never any problems. But recently I wanted to connect another USB-C SSD to my Mini full-time, so I changed to an HDMI to HDMI cable instead.
And something interestiing happened when I did that. My Mini boots much faster with the screen connected to HDMI instead of USB-C. It was taking a long time to boot the Mini with multiple external SSD's connected, the desktop would appear in about 30 seconds but then it could take quite awhile (another 30 seconds or more) for disks and folders to appear on the desktop.
That just doesn't happen with the HDMI monitor connection, the complete desktop appears in under 30 seconds now, the difference is quite dramatic. I suppose this has something to do with the bandwidth needed for the screen as well as the external SSD's? Anyway, I was quite surprised (and pleased) to see the difference.