Hello! You absolutely can, depending on whether you feel comfortable modding the device or not. An iMac's screen isn't special and so just like any other screens you can buy a controller board for it. The controller acts as an intermediary between the monitor and whatever you plug into it. To mount the board in a way that you can easily get to the display ports, the power button, and the menu/settings button will require dremeling the casing of the iMac a bit. I'm debating whether to do this or not to my current iMac or just sell it for a another monitor. I'm tempted to because the dang casing and screen are so beautiful!