I am assuming you are asking this so you can run the game without the bother of putting the CD in and Out and using up battery with the CD Spinning. Not so you take the CD put it on your drive so you can give the CD Back to your friend...
Well if you go to Applications->Utilities->Disk Utility
Put in your CD wait for the Icon to apper Click that Icon then go to File -> New -> Disk Image from ....
and save it as a Master CD. Then it will be on your system. Then you can click the file and it will mount it.... Will the game see it as a CD Rom that is a different issue. Somegames will just make sure that it is accessing files that are in a ISO9660 format While other will be more particular to see if it is actually running form a CD Device. This method will work in the first case.