I used to have 400 or so DVDs ripped to ISO. I was really annoyed that Plex had uneven support for ISOs. I flip flopped between Plex and XBMC (now Kodi) for a long time, and still do. I use Plex for all my remote media consuption, but XBMC for the excellent add-ons and prefer the GUI. Anyway, after converting all my ISOs to mkv (minus the menus), I thought I'd miss them, but I really don't. Physical media is on its way out anyway. Menu systems are going to be a relic soon enough. You can pretty easily create (or copy) a script that will convert all your ISOs to mkvs and the quality can be nearly lossless. 100 movies takes a few days depending on your processing power.
Word.
I guess I'm not worthy..
http://www.htpcbeginner.com/intel-nuc-htpc-media-center/
I didn't know about NUC, glad I do now, been looking for a "little box" that's not ATV..