The screen size remains the same!
I understand that not everybody would be happy with a "phablet-size" screen, due to single hand usability sacrifice but making it at least slightly wider to get to 4.5 - 5 inch display size would have pleased a lot of us.
Home button is still a tactile button, which you can press so eventually it will break/mailfunction after 1000 presses. I find it obsolete, since the fingerprint sensor and the metal ring around are already enough to detect a finger
Camera specs are also slightly disappointing. Despite the bigger pixels, the chip resolution could have been increased as well. You can also merge pixels to reduce noise in low light conditions via software
NFC? No?
64bit CPU: OK, but why not a quad core?
No stereo speakers... I know I'm probably the only one who cries about it...
But the worst thing, among with the tiny display, are the terrible new colors! No slick black, simple white or just bare aluminum but GOLD and Space Grey... ewww.