Out of curiosity, does the STEM software run on Windows ARM? If so, then an M5 MacBook Pro (particularly with the M5 Pro or Max) would be able to run the apps in a virtual machine. Obviously there is the added overhead of a second operating system and shared resources, but it could be done.
Since this is ostensibly a thread about an ARM-based Windows PC, it’s worth discussing how serious Microsoft is about Windows ARM. The Copilot PC experiment seems to have been a failure, at least to date, but as this ASUS PC shows, Qualcomm is capable of designing a very good chip capable of powering a premium PC. But if this or other Windows ARM PCs don’t sell, then there is little motivation for Qualcomm to continue developing consumer-focused ARM processors. With Panther Lake and access to TSMC’s advanced processes, x86-based chips have considerably closed the gap on performance per watt with newer ARM chips. Are there other compelling reasons for Windows ARM to exist?