GPA is going to matter TSE, and that ACT score is not high enough. I would take it again, as well as the SAT. You definitely will want above a 30 on your ACT. I got a 32, and that still would not have been good enough.
Do all that and come to Chicago! You'll love it here.
GPA matters the most from what I gathered, I had a 4.2-4.6 I think and took honors throughout and took AP classes but had an 23 for the ACT and I got accepted in every college I applied for (albeit 2
And yes, Chicago is pretty awesome so far, Depaul is a great school.
Do what I didn't, apply to local colleges, those in the city and the best in the state. Good variety and a good way to note how much money you can get from the school