The best assumption we can make is that the laws of physics we know today are "mostly correct". That means they are close approximations to to nature. In other words we can expect refinments but nothing that would toss out Einstein and Newton in a wholesale way. So no "Star Trek" or "Star Wars" style faster than light communications or travel. OK Maybe I'm wrong but I'd say million to one ods is that I'm not.
That said I think Life is relativly common but tecnology is very rare after all humans have been on Earth for a million years and just invented radio decades ago, Complex life existed for hundreds of millions of years and humans just in the last million. Each milestone between simple life and technology is a one and a million event. But space is big and there might be many civilizations. But space is big and the sppeed of light is not THAT fast, Radio signals from Earth have only traveld less then 100 light years and at that distance we could not detect our own signals. We currently do not have technology to detect a signal except if iti s a "mega transmitter" aimed right at us.
So, while there may be some one out there finding them will not be easy can statistically is unlikely we will find them.
Centuries from now when we do find each other, at first we may be so different that we will not have much to talk about. And it will be painfully slow. We might say "3, 5 and 13 are prime numbers", then 200 years later they say "yes and so is 17" and then it goes on from there.
There is just now way to loose that 200+ year "ping time". We will have to build a robot spacecraft and send it off on a 1,000+ year long trip they mught send one our way
Like I said "Space is big."