Tough to say
I hate to admit it, but from reading other threads and from experience it seems as though you have to do the old Windows Trick... Back up everything and reinstall the OS. Pain in the butt, but I have yet to use any kind of software like Onyx etc. that has been able bring about the same benefits. I am all ears though because it would be nice to not have to do it again... I have a MBP 2007 (July) 2.4 Ghz Intel Core 2 Duo, 4 GB 667 Mhz DDR2 SDRam running 10.5.6, with a 320 GB HD x 5400 Rpm.... and I swear I just can't get to run like the day it came out of the box... :-( I have about 40 GB left of free space. There is also a WinXP partition via Bootcamp I use on rare occasion. Is boot camp slowing down the boot up sequence even when not in use? Seems to work just fine after its 1:40 mins boot up.... roughly 1:40 is when I can start using Apps- after running Onyx and removing Symantec.
Any ideas?