I'd invest in 4+ SATA drive bay vs. single/dual bay. Even as NVMe capacity increases, there will "always" be a need for larger capacity SATA SSD and HDD for the foreseeable future.
Been using this for awhile:
Oyen Digital Mobius Pro 5C 5-Bay USB-C External Drive Enclosure (3N5-C-M)
The Mobius Pro 5C 5-Bay storage system is designed to meet the needs of power users with the most demanding storage requirements. The tray-less design provides a simple method for HDD removal and insertion - simply pull the lever to insert or withdraw the HDDs.
www.amazon.com
Only issue with 2.5" is it needs an adapter like this:
ORICO 2.5 SSD SATA to 3.5 Hard Drive Adapter Internal Drive Bay Converter Mounting Bracket Caddy Tray for 7 / 9.5 / 12.5mm 2.5 inch HDD / SSD with SATA III Interface(1125SS)
www.amazon.com
USB 3.1 10Gbps is more than enough for 550Mb/s SATA SSDs