Here's my set up: Macbook Pro (Early 2010) running 10.6.5 w/ 2.56GHz Intel Core 2 Duo, 4GB DDR3 RAM, 500 GB HD w/ 290GB free space. There have been times when I'm just running iTunes and the wheel of death will come on, or i'm on Chrome or FF w/ 2 other programs running and will get the wheel again and will get locked for about 1-2min. Before I hadn't had too many problems on a different MBP with lower specs, this one is higher yet is slow. I don't understand what the problem is because I also monitor my CPU and when it locks up the CPU remain at normal. Also, flash has always been lagging on here but will freeze for 5-10sec while audio keeps playing. I possibly think it's the Hard Drive which is a WD Blue Scorpio w/ 5400 RPM. Thoughts? I'm thinking of upgrading to 8GB of RAM but think RAM isn't the real issue here. The only heavy programs I run is the Adobe Suite & Maya 2011. Any help is appreciated. Thanks!