I would use the MBA the way I currently use my MB... as a mobile computer to take notes with, occasionally watch/listen to podcasts, chatting, and a little music. Perhaps the occasional simple game like EV Nova or whatnot. I rarely use the MacBook's disc drive, and there's only one USB device I plug into it - my iPod. So technically I could, but I also have a Mac Pro as my primary computer, and I use most of the ports it provides, which neither the MB or MBA can match. The MBA, then, would be a nice secondary computer for me.