Via bootcamped Windows, maybe. Thing is that the Water effects, Shadows and Sun Shafts really drops your FPS way way down in OS X. Probably because the OpenGL version in OS X is subpar to DirectX in Windows atm, it doesn't handle things like that very well at all.
Apart from those three options, you could probably run the rest on Ultra - or at least High. Depending on how much FPS you are comfortable playing with.