A friend of mine that travels a lot told me when I started looking for one of the 'tsa friendly' bags that his doesn't seem to 'work' as tsa still wants him to remove it more often than not... It doesn't seem to work as intended...
So, I got a Gregory backpack where the back section is heavily padded and has top access so I can whip it out pretty quickly and stow it just as fast and it holds a heck of a lot of stuff and yet still fits under the seat in front of me.
I don't know if they still sell it so I will be depressed if it ever wears out. So far, after 8+ years and many trips, it's holding up very well. The straps are padded well and the top handle is heavily reinforced.
There are good bags out there. Given the possibility of having a Barney Fife pulling a hard on for your computer, save the money on tsa friendly and just get a bag you can live with, and afford.
Tom Bihn has some nice bags too...
I just checked, and Gregory doesn't make that bag anymore... Dang... Now I hope it lasts a long long time...