Twice today I replied to an email using the me.com webmail interface...2 different recipients, hours apart. I clicked reply, typed the reply, clicked the paper airplane icon, the message appeared to be sent, the inbox refreshed onscreen. But the "replied" arrow icon next to the email I was replying to was not there. Looking in the sent box it was nowhere to be found. It wasn't in any mailbox, trash, junk, etc. Poof. A lengthy reply at that. I verified with the recipients that they received no reply from me. If it happens once, it's most likely user error; twice and it's a glitch. MobileMe support said it was a known issue around the launch but should have been remedied by now. No kidding. This hasn't happened to me up until today. The only difference I can think of between today and any other time I've used me.com is that the computer I'm on today is running Leopard instead of Tiger like I use at home. Both have the latest version of Safari however. Just a heads up...who knows if it will happen to others. My plan is to copy my reply to the clipboard before sending from now on. *EDIT* it just happened a 3rd time.