That said, as osx becomes more popular as I am sure it will, I think the virii will appear.
I think there is some truth to the windows mindset but I also believe that if the same number of malicious folks were looking at osx code for vulnerabilities, there will be some that get uncovered.
Eventually I'm sure someone will figure out how to write the first virus for OS X. It hasn't happened yet in 10 years, but that's not to say it couldn't happen tomorrow.
However, until that happens, any antivirus software you run today would have nothing to go on as far as detecting it, so it's pointless either way.
Plus, the first Mac virus outbreak will be huge headline news in the tech world ("It's finally happened!" etc.) So unless you were one of the very first people infected, you'd probably have plenty of warning.
In short: for now, "careful computing" is all you need. Don't install anything you didn't specifically download yourself (like that auto-downloading "Mac Defender" trojan everyone was talking about yesterday), don't give your admin password to programs without thinking about why they might need it, don't download things from shady sites. That'll cover you for malware, which is right now the only real threat that exists on OS X.