No. I love my iPad and use it very regularly when I'm both at home and out and about, but there is no way it can replace my MacBook Pro. In fact, I'd go as far as to say it's likely a touch screen device will never be able to replace my full featured notebook.
We have a MBP 17" that stays at home as our main machine for heavy work. I had an MSI Wind running OSX that was my 'go everywhere' machine, but sold that to help finance the iPad and don't miss it one bit.
Jobs was right - maybe a netbook really isn't good at anything...
But I'm still considering purchasing one of the refreshed Macbooks to have a more capable travel machine with me.
The iPad still needs a "mothership" to operate. I am debating whether that mothership needs to remain my desktop or my laptop. The laptop can still run circles around the iPad in terms of functionality, so no, I don't see it as a replacement.
Not me . . . I'm holding onto it for sites that require flash and to update my Harmony Remotes (Mac software is rather unstable). Other than that I rarely touch my netbook. I also traded in all of my portable gaming systems and games. I don't touch those anymore either. Guess I can safely say that the iPad has rendered the rest (iPhone not included) of my portable electronics useless
Sold my HP netbook, but still have an Asus eee netbook (for the kids' games that require Windows), and a MacBook Pro which is pretty stationary now. I could travel exclusively with the iPad if Keynote did a better job (see my review here) but for now, I prefer presenting from a MacBook.