I hate to tell you this but when you're sitting in front of your screen for 10+ hours a day looking at 11pt text in an IDE, yes, those two images actually make a massive difference.
One means I can get to the end of the day and feel like I can still see correctly, the other my eyes are straining by about 6 hours.
Something to also consider is that you can actually have an even bigger visual difference than that if using higher DPI still and no matte screen. One of the common comments from users of Dell's 8K UP3218K is that, despite having a 280 PPI density, smaller text is still surprisingly readable even with modest scaling.