No issues with my Caldigit Audio, or Daytonaudio going to my speakers from the optical interface of my Caldigit on my new MBP.
This worked somewhat for me. Given that it is not bus-powered, I had issues when the computer woke back up from sleep. Sometimes audio would go out, but the Mac would think that the device was still plugged in. It was all very strange and not 100% rock solid. This Cable Matters powered thunderbolt 3 hub has been best cheapest option for 100% operation: https://www.amazon.com/Certified-Cable-Matters-Thunderbolt-DisplayPort/dp/B01DYFHYNS
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