Yes!! All of the sudden (seemingly randomly) the whole Desktop would lag (moving windows, opening closing them,...) Like the video you posted!
So I did another partition and installed a fresh Catalina on it. Everything worked better until i installed the Wacom drivers. The lag came back. That was my clue! From there a Google search lead me to this
And voilà!
It's crazy but I feel like it's another computer. It's super smooth.
To those of you using a Wacom with the Macbook Pro 16, DO NOT install their latest drivers (6.3.38-3)!!!!