And the price?
Well it depends on how much you want to spend
Spend more and it'll sound better. However, there are solutions which costs the same (or are cheaper) than others which sound just as good or even better. Then you are refering to the Price/performance ratio.
I think it's a good idea to post only speakers/audio solutions which have an excellent price/performance ratio. I saw things here of >20,000 dollars, now that's not a good price/performance ratio unless you are going to build a cinema or organize your own festival.
To mention some speakers which have a good price/performance ratio:
Creative Gigaworks T40, Corsair Gaming Audio SP2500, M-studio Audiophile AV40, Harman Kardon Soundsticks III, AudioEngine (any), Swans (any, however M10 are worth to mention), Logitech Z5500, Logitech Z2300, Focal (any), Bose Companion 5, Razer Mako 2.1, Teufel (any, however the Concept B 200 USB are worth to mention),...
Also worth considering is a DAC or amplifier, or why not both?
I have a Maverick Audio D1, which is a DAC, Headphone amplifier and tube amplifier in 1, for 199 dollars. Now that's a bargain. Sounds terrific, and has Optical, Coaxial, USB and analog inputs. I use it with a Creative Gigaworks T3 (which has too much bass

) and Sennheiser HD595 headphones (heavenly

)