Just an FYI regarding booting my mid-2011 27" i7 from the new 256GB LaCie Rugged Thunderbolt SSD. In short, it works perfectly so far, and no surgery required (edit; 13 months - rock solid through may sleep cycles.). It wakes from sleep without issues. I cannot tell any real difference from an internal SSD. I use SuperDuper to mirror the SSD to the old HD boot partition once a week (in addition to TM and my other backups...). I'll report back periodically with updates. I also enabled TRIM using Trim Enabler and a re-boot... Blackmagic 1GB: W 250 MB/s R 378 MB/s (HDD ~90 and 95) Boot Time to Login: 19.4s (was 90.1s with HDD) Lightroom 4.2: 4.1s (was 14.7s) Parallels XP Boot: 9.4s (was 45.8s) iPhoto: 4.7s (was 14.7s) Photoshop Load: 5.3s (was 12.7s) While not as fast as a best in class internal 6GB SATA3 SSD, it's certainly an easy way to move to an SSD environment. I just rubber banded the drive to the back of my iMac after removing the orange bumper. No power required. This is a cheaper and more compact external 256GB option than the GoFlex STAE122 + SSD + cable combo (~$420). The LaCie is $349 including the TB and USB3 cables.