Since I'm aiming to keep this machine for the next 5 years, gotta be sure I made the right decision
All I would say, if it is going to be in use with you for half a decade then spend the extra and get the 16GB and 750M or you'll spend the next five years wishing you had. Even if Iris Pro pulls ahead in obscure OpenCL environments - of which I am slightly skeptical then you can just disable the dGPU, aside from cost there isn't a downside.
Half the people on here that are going a bit nutty over Iris Pro vs 750M need to realise unless they are gaming I doubt any of them would notice. These systems have very capable CPU's, plenty of RAM (providing you opt for it) and great overall hardware. Ever since Sandy Bridge I've felt processors have become more than fast enough, now Intel realises that and wishes to spearhead into the lower TDP field that ARM dominates we are seeing very powerful chips with relatively low power requirements. I feel providing you get your rMBP with atleast 8GB of RAM then you'll be fine.