On my 2011 MacBook Pro, upon reboot after the upgrade, Bluetooth was pretty messed up. I have 5 devices paired, and typically use 3 when I'm in desktop mode (Apple Trackpad, Apple Keyboard, Apple Magic Mouse). All indicated they were connected. The Magic Mouse was unresponsive, the trackpad would only move the cursor in a horizontal straight line in a jerky motion, and the keyboard was flaky (slow, untyped characters showing in output). The console log was full of bluetooth error messages.
I turned Bluetooth off, and back on, and power cycled each of the Bluetooth devices. No change.
I decided to remove everything from the Bluetooth preference pane, and got a kernel panic when i tried to remove the last device, the trackpad.
Booted from the Diskwarrior DVD and ran a check on all drives. Disconnected the machine from the "docked" state and booted it by itself. Everything worked fine without any Bluetooth devices connected. Removed the trackpad configuration. Turned Bluetooth off.
I reset PRAM and SMC, turned Bluetooth back on, and successfully paired my Jambox Jawbone and Jambox ERA. They work fine; even better than with 10.7.1. I've yet to re-pair the Apple devices, but it would seem at this point it might have been a temporary state, or something in the configuration that didn't match well with a bug fix. I'll know more when I muster up the courage to try the system "docked" again.
Other than that, everything is working well.
Update: Re-pairing the remaining Bluetooth devices worked without issue. Everything's working fine now.