What blood types get more reactions to the vaccine ???
Recent warnings by the medical community says not to use ibuprofen before and after vaccines as they tend to suppress the immune response to create antibodies.My wife got her second dose(Pfizer) last week.
She took ibuprofen before and for a day after. It swelled up to a heck of a knot on her shoulder, more so than the first one, but no fever or other issues sometimes reported.
She has been rediculously tired the last couple days since getting it, and she's wondering if it's from the shot. Still, though, she was happy to get it and I'll certainly be rolling up my sleeve when my turn comes.......
Recent CDC guidance has changed the time period window for 2nd doses to up to 6 weeks:Well I can’t get an appointment for my second shot. Only places available are 45 minutes away and nothing available when I could do it. Guess I’m not getting my second shot.
This has been disappointing. Got my 1st local and now they say drive to the other side of the state. Pass thanks
Good to hear from a survivor - how was it - mild, moderate, severe ?Having just had covid-19 ... I hope everyone can get the vaccine soon!
Moderna vaccinations here. (Both completed.) No issues.
My wife is a cardiologist and had her second vaccination last week, no issues. We’re both in our mid 30’s.
[Anecdotally, I have to agree with an infectious disease doctor that she works with, and said that some reactions are worse depending on which blood type you are.]
Really ?
What blood types get more reactions to the vaccine ???
Actually it’s 80-90% effective.
https://amp.wbur.org/commonhealth/2020/12/18/coronavirus-vaccine-single-dose-debate
Agree, but how is the LONG TERM immunizing ability of mRNA vs DNA ?
I know there hasn't been enough time to monitor presence of the anti spike proteins due to the emergency use authorization compared to conventional vaccine testing....
Do you expect we will need boosters or new vaccine shots every year or less ??
The J&J adenovirus DNA delivery design seems like it would last longer due to the stability of DNA vs RNA ???
I’ve decided to get the 2nd dose. Planning on a long weekend. Getting it on the 26th.The problem with the single dosing plan is that there is insufficient research on how long this level of immunity is sustained longterm. It's nice to know that a single dose has 80% efficacy on day 14, but what about down the road. Without having solid evidence that the 80% can be sustained, I think it's risky decision to make, but I understand the ethical implications in terms of being able to vaccinate more people, faster. There is a reason Moderna decided to use a two dose course, I'm not entirely sure what evidence specifically lead them to that choice. I would assume there is some Phase I/II or pre-clinical data to support this decision.
I don't think it's wise to alter the dosing when we don't have the evidence to backup the decision. I definitely think it's something that should be investigated however (and is). Only looking at efficacy and antibody levels 2-4 weeks down the road though does not provide the information necessary to extrapolate into longterm efficacy.
Yes, no one knows for sure and we will have to monitor this. While mRNA vaccines are new to the market, they have been researched for quite some time. Both Moderna and Pfizer project 2-3 years of immunity, but of course there's no way to truly know for their respective vaccines until we can make those observations. Looking at some of the DNA vaccines on the market, they seem to last at least 10 years, but that doesn't mean that's what to expect with COVID as these existing products are for very different viruses.
DNA is the longterm storage format of genetic material. DNA creates mRNA, which is basically a temporary copy and therefore not as durable (m = messenger). The mRNA is then used as the template to create the viral spike protein, which the immune system then recognizes as bad and immunity is formed. Basically DNA and mRNA vaccines work the same, the DNA vaccines just start one step back by inserting the DNA into the host cell nucleus. Once the cell is manufacturing the viral proteins and the immune system recognizes these as foreign, it will mark the infected cell for destruction destroying everything, including the viral DNA, ending the ability for more proteins to be formed. So it's a little difficult for me to see why a DNA vaccine would somehow last much longer. Hopefully I explained that in a digestible manner.
I think it's possible we may have to get yearly vaccines. But if we have 95% efficacy, that may not be necessary. It may take several years and boosters to get there, but I am optimistic. The virus does not mutate particularly well, but up until now there has been virtually no natural pressures for the virus to mutate (ie immunity). So we'll have to see how new strains arise and how well the vaccines work against them.
And just to point out, you’re not the only one that’s considered just getting only 1/2 of the vaccinations. I suspect others are in your position that sometimes can read too deep on the ‘internet files’ into the effects of the second dose where it can be over-bearing. Just focus on hydration, rest and you’ve got a game plan where you don’t have a ‘heavy work’ load that follows your 48 hour recovery.I’ve decided to get the 2nd dose. Planning on a long weekend. Getting it on the 26th.
I chose Friday as I have the weekend off. I work in healthcare. So I’m well informed. Most of my hesitation is my huge phobia of injections. Not needles but the injection part.And just to point out, you’re not the only one that’s considered just getting only 1/2 of the vaccinations. I suspect others are in your position that sometimes can read too deep on the ‘internet files’ into the effects of the second dose where it can be over-bearing. Just focus on hydration, rest and you’ve got a game plan where you don’t have a ‘heavy work’ load that follows your 48 hour recovery.
Best.
That’s interesting, I’ve never come across somebody that’s been concerned with the injection part, usually the sight of needles in general. But I think people are starting to figure out now with the recent side effects from dose 2, to give yourself at least two days off post injection, versus having the ‘I’ll work through it’ type of attitude. It’s just a safe bet.I chose Friday as I have the weekend off. I work in healthcare. So I’m well informed. Most of my hesitation is my huge phobia of injections. Not needles but the injection part.
Guess I’m weird. But the stick is nothing. When they push the plunger I feel like I may faint. Never have but I usually just sit down.That’s interesting, I’ve never come across somebody that’s been concerned with the injection part, usually the sight of needles in general. But I think people are starting to figure out now with the recent side effects from dose 2, to give yourself at least two days off post injection, versus having the ‘I’ll work through it’ type of attitude. It’s just a safe bet.
I know this sounds kind of juvenile, but have thought about listening to music while they start the injection? By doing that, it’s more of a mental distraction that you can’t really hear what’s going on and you don’t get the prompt from the nurse like ‘Are you ready?’ I’m not saying that would work for everybody, but it might be a temporary remedy where you listen to one of your favorite songs that optimistically put you in a different vibe and overall cause that distraction within those 3-5 seconds.Guess I’m weird. But the stick is nothing. When they push the plunger I feel like I may faint. Never have but I usually just sit down.
Blood draws dont bother me in the least. In fact I can and have drawn my own blood.
Wouldn’t work for me. I know what they are doing. I feel the stick and know what’s coming. I’ve given many injections also so. I just ask to be seated and usually grab the side of the chair with my other hand and squeeze. Eyes are closed the entire time. Grimacing the whole time. Always get asked if I’m ok.I know this sounds kind of juvenile, but have thought about listening to music while they start the injection? By doing that, it’s more of a mental distraction that you can’t really hear what’s going on and you don’t get the prompt from the nurse like ‘Are you ready?’ I’m not saying that would work for everybody, but it might be a temporary remedy where you listen to one of your favorite songs that optimistically put you in a different vibe and overall cause that distraction within those 3-5 seconds.