With the 3.5/4.0" iPhones, either hand. With the 6 Plus, hold it with left hand and operate it with right hand or just use both hands to hold and operate. It's just too big for me to hold and operate one-handed.
Right handed. I hold my phone in my left hand and use my right hand for apps I can't reach one handed. For a moment, I thought I read "guys, which hand do you use for...". Too many glasses of red wine this evening.
Right-handed, but I usually hold it in my left hand. And for some crazy reason, even with the regular landline phone, I have never been able to use it on my right ear, always has to be my left ear. Don't know why.