With two iPads and an iPhone I tend to sync both with iTunes and in iCloud...... When I get notification of a bunch of app updates, I first download into the computer, and then I sync each device individually (usually wirelessly). If I've added a bunch of new music recently I also will sync the old iPod Classic that I use primarily in the car, too. After everything has been synced with iTunes in the computer, I then also sync/backup to the Cloud as well. Covers all bases!