FYI - Facebook already did. All new videos are supposed to be in HTML5 now.
I'd also like to know what the OP wanted to do and can't.
I've been able to FTP files to my server and edit HTML files (FTPontheGo), log into my desktop computer at home (Mac) and at work (Windows) using LogMeIn Ignition, draw with various drawing apps (ArtStudio, Sketchbook, Layers, Brushes), take notes in a meeting with GhostWriter (and looking forward to Notetaker HD), write and send a document in Pages, browse the web, email, text (TextPlus), edit a few photos (PixelMagic, Photogene or PhotoPad) listen to music, watch a few youtube videos, enjoy a netflix movie, rewatch the latest episode of "Lost", read RSS feeds, subscribe to a few magazines, buy a few books (and download a few free ones), use GoogleMaps and the built-in GPS to explore a new area... oh, and go ALL F'in DAY without needing to plug the device in! LOL