My Launch Day iPhone 4 had the mysterious battery drain problem as well. Its a shame Apple did not fix the problem this time around.
I would charge my phone to 100%. Remove phone from charger. Power off (not standby). Turn it on in the morning 8 hours later. Battery down to 50%. Apple's 'diagnostic' program said the battery was fine, but the Genius noticed it draining while we spoke. They replaced the phone with a brand new one.
I would charge my phone to 100%. Remove phone from charger. Power off (not standby). Turn it on in the morning 8 hours later. Battery down to 50%. Apple's 'diagnostic' program said the battery was fine, but the Genius noticed it draining while we spoke. They replaced the phone with a brand new one.