I'm optimistic that the GPU will be user-upgradeable and not use a proprietary design. The reason for this is Apple was not going to do a new Mac Pro. The iMac Pro was to be the next top-end Mac to carry the line forward and the trash can would have been end-of-lifed and not replaced.
That Apple has now changed their minds to give us a new Mac Pro is, IMO, solely due to the iMac Pro not being fully upgradeable just like the 2013 Mac Pro was not and a realization / acceptance that this lack of upgradeability is not acceptable to the majority of people willing to pay the prices Apple charges for such a product. Therefore Apple has to make the component that changes the quickest - the GPU - user-upgradeable.
To make the Mac Pro's GPU non-upgradeable serves no purpose. Even if you believe Apple would do so out of spite (and unfortunately plenty of people seem to believe that), this model is not going to sell very many (as a percentage of all Mac desktop sales, much less all Mac sales) if it is very upgradeable. If it is not, it's not going to sell at all and Apple has better things to do with their money than make a product that will not sell just to spite the "haters".